Though less typical, by far the most major Unwanted side effects of ursodiol are described beneath, coupled with how to proceed should they happen. Nonabsorbed ursodiol passes into the colon where it is mostly 7-dehydroxylated to lithocholic acid. Some ursodiol is epimerized to chenodiol (CDCA) through a seven-oxo intermediate. https://www.youtube.com/watch?v=A07qHOeWON8