Butabarbital will reduce the level or impact of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Influence of coadministering a powerful CYP3A4 inducer with fedratinib hasn't been researched. butabarbital will decrease the level or influence of estrogens esterified by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/... https://stevek899urn6.eedblog.com/profile